Laugierhunziker syndrome lhs is an infrequent disorder, characterized by brown macular hyperpigmentation as a grayish brown lentiginous macules of about 5 mm, of the lips and oral mucosa. A histologia e tipica, com amplo diagnostico diferencial. Laugierhunziker syndrome abstract laugierhunziker syndrome is a rare acquired pigmentary disorder that is characterized by idiopathic mucocutaneous pigmentation that may be associated with longitudinal melanonychia. Laugierhunziker syndrome is an extremely rare disorder but is of some interest to dental practitioners. If you do not have it you can download adobe reader free of charge. Pdf most of the documents on the racgp website are in portable document format pdf. The table summarizes the 25 cases published in the last decade 20072017 in the scientific literature in english available at pubmed 121.
Laugierhunziker syndrome is a benign mucocutaneous pigmentary disorder that mainly affects the oral mucosa and nails. Lhs is a rare condition of unknown pathogenesis, with a limited number of reported cases since its first description in 1970 6, 7. Oral manifestations of idiopathic lenticular mucocutaneous. Michelle hunziker nasce nel 1977 a sorengo, nella svizzera italiana, da madre olandese e padre svizzero. Laugier hunziker syndrome is an idiopathic, acquired, benign, melanotic hyperpigmentation of the lips and oral mucosa, which is often associated with a longitudinal pigmentation of the nails.
It is a diagnosis of exclusion, and other systemic conditions should be excluded prior to making a diagnosis. Citescore values are based on citation counts in a given year e. Laugierhunziker syndrome in endocrine clinical practice in. Case report cihangir aliaaolu, mustafa atasoy, ozgul balk onder. Laugierhunziker syndrome is an infrequent benign and acquired condition of the lips, oral mucosa and nails. Laugierhunziker syndrome is a rare acquired disorder characterized by diffuse hyperpigmentation of the oral mucosa and longitudinal melanonychia in adults. A k lampe, p j hampton, k woodfordrichens, i tomlinson, c m. Dermoscopic findings in laugierhunziker syndrome dermatology. Two of these patients also displayed pigmentary changes of the nails. Laugierhunziker syndrome is an acquired macular hyperpigmentation of the oral and genital mucosa, often associated with longitudinal melanonychia. Pdf laugierhunziker syndrome is a rare acquired disorder characterized by diffuse hyperpigmentation of the oral mucosa and. Read oral manifestations of idiopathic lenticular mucocutaneous pigmentation laugier.
Regezi, patologia oral 6edicao by elsevier saude issuu. There was no knowledge of intestinal polyposis or stomach, intestine or colon cancer in her family. In 1970, laugier and hunziker1 reported on 5 cases of essential melanotic pigmentation of the mouth and lips. These files will have pdf in brackets along with the filesize of the download. Laugierhunziker syndrome lhs comprises benign mucosal pigmentation in the absence of gastrointestinal pathology. The importance of the condition relates to it being included in the differential diagnosis. The laugier hunziker syndrome lhs is an acquired, benign pigmentary skin condition involving the oral mucosa, often associated with longitudinal melanonychia. Laugier hunziker syndrome is a rare, acquired pigmentary disorder of the lips, oral mucosa, and nails. Hyperpigmentation mimicking laugier syndrome, levodopa. Jun 27, 2019 laugier hunziker syndrome lhs was initially described in 1970 as acquired, benign hyperpigmented macules of the lips and buccal mucosa frequently associated with longitudinal melanonychia. Laugier hunziker syndrome is an extremely rare disorder but is of some interest to dental practitioners.
Laugier hunziker syndrome is a rare, acquired disorder characterized by lenticular hyperpigmentation of the oral mucosa and longitudinal melanonychia. Laugier hunziker syndrome lhs is an acquired pigmentary condition affecting lips, oral mucosa and acral area, frequently associated with longitudinal melanonychia. They appear as macular lesions less than 5 mm in diameter. We present the case of a 63yearold female with progressive, asymptomatic hyperpigmentation of buccal mucosa and a 7year history of hyperpigmentation in several fingernails. Laugier hunziker syndrome an overview sciencedirect topics. Melanotic macular hyperpigmentation has been observed on the neck, the thorax, the abdomen, the dorsal and lateral aspects of the fingers, the palms and soles, the genitalia, the perineum, the perianal skin, and the anal mucosa of patients with laugier hunziker syndrome. Arrivata in italia, comincia giovanissima a cercare occasioni di lavoro presso le agenzie di modelle di milano. Laugierhunziker syndrome is considered to be a benign disease with no systemic manifestation or malignant potential. Backgroundlaugierhunziker syndrome lhs is a rare, acquired mucocutaneous hyperpigmentation often associated with longitudinal melanonychia. Hyperpigmentation in laugierhunziker syndrome cmaj.
Summary laugier hunziker syndrome is an infrequent benign and acquired condition of the lips, oral mucosa and nails. Jun 27, 2019 extended mucocutaneous pigmentation has become a recognized feature of laugier hunziker syndrome. Laugierhunziker syndrome is a rare, acquired disorder characterized by lenticular hyperpigmentation of the oral mucosa and longitudinal melanonychia. Laugier hunziker syndrome lhs is a rare acquired benign macular hyperpigmentation of the lips and oral mucosa which is often associated with longitudinal melanonychia. To open a pdf file you will need compatible software such as adobe reader. We read with interest the case and research letter by marcoval et al. Laugierhunziker syndrome lhs is an acquired, benign pigmentary skin condition involving oral cavity including lower lip in the form of brown black macules.
We were surprised that the letter did not mention laugier disease or laugier hunziker syndrome, an entity characterized by essential cutaneous and mucosal pigmentation, originally described on the lips and oral mucosa and, at times, associated with. Pigmented fungiform papillae of the tongue in laugier disease. In followup over the next five years, an increasing number of pigmented macules was noted. Oral presentation of the laugierhunziker syndrome british.
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